Histoneacetylation相关论文
Dynamic profiles of DNA methylation and the interaction with histone acetylation during fiber cell i
Background: Fiber, as the main product of cotton, provides main raw material for the textile industry. Many key factors ......
Histone deacetylase inhibitor scriptaid improves the in vitro development competence of sheep somati
Since the first clone sheep "Dolly" was produced by somatic cell nuclear transfer (SCNT) technique,the success rate of......
Treatment with Oxamflatin Modifies the Epigenetic Status of In Vitro Porcine Somatic Cell Nuclear Tr
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Epigenetic Modification Regulates the Attention Deficit & Hyperactivity Disorder Associated with Lea
Attention deficit & hyperactivity disorder (ADHD) was a common neurobehavioral disease defined by inattention, hyperacti......
Arsenic metabolism and arsenic-induced epigenetic modifications:the role and implication for arsenic
Consumption of drinking water contaminated with arsenic, a natural and carcinogenic metalloid, constitutes a global publ......
Inhibition of NF-κB-dependent CX3CL1 upregulation attenuated the central sensitization and acute pai
Background:Acute and chronic painful peripheral neuropathy following the oxaliplatin treatment is the principle dose lim......
Integrin αV is important in promotion of anchorage independence,angiogenesis and cancer metastasis,but its regulation i......
Cuticular wax is a major composition of plant surface cuticle,which exerts crucial functions in optimizing plant growth.......
Auxin Response Factors Control Identity of Apical Stem Cell Niches by Regulating Histone Acetylation
Auxin is critical in diverse developmental processes,such as the maintenance of shoot and root meristems.AUXIN RESPONSE ......
Several transcription factors that regulate growth-associated genes undergo lysine methylation,expanding the repertoire ......
Background & Aims: Although numerous long non-coding RNAs (lncRNAs) have been identified in mammals, many of their biolo......
Epigenetic Activation of MiR-200Family Contributes to H19mediated Metastasis Suppression in Hepatoce
Recently,long non-coding RNA is thought to be contained in human genome as important regulatory transcripts in which we ......
The Histone Deacetylase4/Sp1/miR-200a Regulatory Network Contributes to Aberrant Histone Acetylation
As an important epigenetic mechanism,histone acetylation modulates the transcription of many genes and plays important r......
The role of histone acetylation in the regulation of the initiation of DNA replication in Saccharomy
The accurate regulation of the initiation of DNA replication in eukaryotic cells is a key study in gene expression,and t......
Background: Congenital heart diseases (CHD) remain the leading cause of death related to birth defects.A transcriptional......
The drug-associated conditioned stimulus (CSs) come to influence drug-seeking and relapse behaviour through the memories......
Islet-1 Promotes Cardiac Specific Differentiation of C3H10T1/2 Cells through Histone Acetylation Reg
Objective To investigate the effect of Islet-1 on the process of mesenchymal stem cells (MSCs) differentiation into card......
Hexavalent chromium(Cr(Ⅵ))is a potent human lung carcinogen,and numerous epidemiological studies have been performed to......
Histone deacetylation and acetylation status in memory T lymphocytes relates to allergen-induced eos
Background and objective:T lymphocyte,characterized by longevity and immune memory,play an important role for recurrent ......
Exposure to hypobaric hypoxia(HH)cause multiple aspects of neuron cell damage,and consequently result in the impaired co......
Effect of chronic cerebrovascular hypoperfusion on global DNA methylation and histone acetylation in
Objective DNA methylation and histone acetylation can be modified by variety of pathological or physiological factors, s......
Oxidative stress and inflammation as the pathoogical components of Alzheimer s disease (AD) have been well understood.Am......
BACKGROUND: Influenza A virus(IAV)replicates in the nucleus and assembles in the cytoplasm.The detailed intracellular pr......
Upregulation of NLRP1 Inflammasome by STAT3 Activation and STAT3-dependent Histone Acetylation in DR
Background.Bortezomib(BTZ)is the frontline chemotherapeutic drug for multiple myeloma.However,BTZ carries a severeside e......
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Melanoma originates from epidermal melanocytes and is the most malignant form of skin cancer,with an increasing incidenc......
全身麻醉药对发育期大脑具有潜在神经毒性作用。组蛋白去乙酰化酶抑制剂（histone deacetylase inhibitors, HDACIs）可通过提高细胞内......
Epigenetic modification regulates developmental lead exposure induced Attention DeficitHyperactivity
Lead(Pb)exposure was commonly considered as a high environmental risk factor for the development of attention-defici......
目的研究丁酸钠对Wistar大鼠酒精觅药行为及海马NMDA受体2B亚基(NMDA receptor 2B subunit，NR2B)基因启动子区H3K9乙酰化表达的影响......
精神疾病是一类遗传和环境因素共同作用所致的疾病，而表观遗传学是衔接环境暴露与遗传背景之间的桥梁。为探讨表观遗传修饰与精神疾......
儿童早期的视觉经历对视觉皮层神经环路和可塑性的形成及巩固起着重要作用，长期的视觉经历对皮层可塑性的影响与细胞内信号分子通路......
砷是一种重要的类金属元素，广泛分布于自然界中。它对身体健康的危害是多方面的，但目前，砷毒性作用机制尚未完全阐明。近年来，很多研究......
目的构建人原代成骨细胞体外氟中毒模型，观察不同剂量氟化钠（NaF）对人成骨细胞细胞周期蛋白D1（CyclinD1）、细胞周期蛋白依赖性激酶4（CDK4......
AIM: To investigate the effect of histone acetylation on regulation of p21WAF1 gene expression in human colon cancer cel......
Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of
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Expression of p21WAF1 is related to acetylation of histone H3 in total chromatin in human colorectal
AIM: To explore the relationship between acetylation of histone in total chromatin and p21WAF1 expression regulation in ......
AIM:To investigate the effects of butyrate on interleukin (IL)-32α expression in epithelial cell lines. METHODS: The hu......
Objective: Multiple myeloma is a kind of malignant plasma cell disease that originated from B lymphocyte and secrete gre......
Three functionally redundant plant-specific paralogs are core subunits of the SAGA histone acetyltra
The SAGA(Spt-Ada-Gcn5 acetyltransferase)complex is an evolutionarily conserved histone acetyltransferase complex that ha......
A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation
In eukaryotes, histone acetylation is a major modification on histone N-terminal tails that is tightly connected to tran......
为研究生肌素在染色质重建过程中的作用,采用生肌素真核表达载体转染C2C12肌细胞,细胞核经微球菌核酸酶消化后,提取DNA进行SDS-PAG......
